Attempt this previous-year question. The correct option stays hidden until you choose.
Which of the following statements with regard to genetic medicine is/are correct ?
1. Genetic medicines correct/compensate for the faulty genes responsible for disease.
2. Engineered viruses and lipid nanoparticles are used as carriers of the genetic medicine.
3. Genetic medicines alter the entire DNA sequence.
Select the answer using the code given below :
Pick an option to check yourself.
- **Correct Answer:** (c) 1 and 2 only
- **Statement 1 is correct:** Genetic medicine (gene therapy) aims to treat diseases by introducing, removing, or altering genetic material within a patient's cells to correct or compensate for faulty genes that cause dysfunction.
- **Statement 2 is correct:** Delivery systems are crucial for genetic medicine. Engineered viruses (like AAV or lentiviruses) are used for their natural ability to infect cells, while lipid nanoparticles (LNPs) are synthetic carriers used to protect and deliver genetic payloads (like mRNA) into cells.
- **Statement 3 is incorrect:** Genetic medicines do not alter the *entire* DNA sequence of an organism. They are highly specific, targeting only the relevant gene or sequence associated with a particular disease. Altering the entire DNA sequence would be catastrophic and is not the goal of therapeutic gene editing or replacement.
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